Folic acid is the most common form of folate supplements. Once ingested, your body is supposed to convert folic acid, a synthetic version of folate, into 5-methyltetrahydrofolate, or 5-MTHF. But research shows that many people lack sufficient activity of the enzyme that’s necessary to convert folic acid to 5-MTHF. A more useful approach is to take 5-MTHF directly.
5-MTHF, homocysteine & cardiovascular health
Folate helps maintain healthy homocysteine levels already within the normal range. By helping to inhibit excess homocysteine, folate supports healthy levels of this important cardiovascular health biomarker. And 5-MTHF has been shown to be more bioavailable than folic acid in some studies.
5-MTHF, homocysteine & cognitive health
5-MTHF’s greater bioavailability is especially important for people who don’t have enough activity of the enzyme necessary to convert folic acid to its biologically active form. Since people with elevated homocysteine levels have a greater risk of cognitive decline, the increased efficiency of 5-MTHF in supporting healthy folate status is especially crucial for aging individuals.
Take alone or with B12 for enhanced effect
The RDA for folate for non-pregnant or lactating adults is 400 mcg a day, but this high-potency formula provides 5,000 mcg of this super-bioavailable form of folate. For even greater health benefits, take 5-MTHF folate with methylcobalamin (the active form of vitamin B12), vitamin B6 and/or riboflavin.
|Serving Size 1 vegetarian tablet|
|Amount Per Serving|
|Folate [as (6S)-5-Methyltetrahydrofolate, calcium salt]||8,500 mcg|
Microcrystalline cellulose, dicalcium phosphate, stearic acid, croscarmellose sodium, silica, vegetable stearate.
Take one (1) tablet daily with food, or as recommended by a healthcare practitioner.
Caution: Do not use this product if treated with methotrexate, fluorouracil, phenytoin, phenobarbital, primidone, or levodopa prior to consultation with your personal physician.
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When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.